Detroit Mob Confidential explores the history of Detroit's La Cosa Nostra Family, which, in many ways, is the most successful crime family in the United States. Detroit's family has had only 2 Dons, the current boss has served for 30 years and is the longest serving mob Don in America. The documentary consists of interviews with multiple FBI agents and Federal prosecutors as well as several mafia associates from the 1950's and 1960's. Topics such as the Detroit "Combination's" (as the Family is known) infiltration of Las Vegas casinos and their centrality to the disapearance of Jimmy Hoffa are discussed.

“White Boy Rick”, as he was called, was a novelty: A white teenager seemingly running a major inner-city drug operation. In May of 1987, 17-year-old Richard Wershe Jr. was charged with a non-violent, juvenile drug offense. By the time of his arrest he was already a Detroit legend, frequently making front-page headlines and leading the local television news. In this film, gangsters, hit men, journalists and federal agents struggle to explain why he remains in prison at nearly 50 years old. The possible explanation is more stunning than the crimes Wershe was alleged to have committed.

The story of how Detroit, once considered the heart of the American Dream, lapsed into the country’s crime capital as its auto industry crumbled.

A reputed Detroit drug kingpin who once staged his own kidnapping and assassination to disappear for several months, was killed.