The ghost of "patient zero", who allegedly first brought AIDS to North America - materialises and tries to contact old friends. Meanwhile, the Victorian explorer Sir Richard Burton, who drank from the Fountain of Youth and now works as Chief Taxidermist at the Toronto Natural history Museum, is trying to organise an exhibition about the disease for the museum's "Hall of Contagion".

Navy SEAL Shane Wolfe is handed a new assignment: Protect the five Plummer kids from enemies of their recently deceased father -- a government scientist whose top-secret experiment remains hidden in the kids' house.

In a small town on Christmas Eve, a snowstorm brings together a group of young people. They soon find their friendships and love lives colliding, and come Christmas morning, nothing will be the same.

When a man, beaten and bloody, stumbles into the law office of Charlotte Saint John, she discovers that he has amnesia. She takes him in as a guest, hoping that his memory will recover once his wounds heal. While she helps nurse him to health, the two start falling in love. But everything changes when his wife comes to get him. When another woman comes forward claiming to be Jay's wife as well, he's put on trial for bigamy and Charlotte defends him.