Francis and Blake Falls are Siamese twins who live in a neat little room in a rundown hotel. While sharing some organs, Blake is always fit and Francis is very sickly. Into their world comes a young lady, who turns their world upside down. She gets involved with Blake, and convinces the two to attend a Halloween party, where they can pass themselves off as wearing a costume. Eventually Francis becomes really ill, and they have to be separated. They then face the physical and mental strains that come from their proposed separation.

Trevor Blackburn is accused of murdering his girlfriend, Faith, in a brutal ritual. He's sentenced to live in an experimental rehabilitation community and falls into a coma. When he wakes up, he meets the mysterious Dr. Ek, who tortures Trevor in an attempt to learn the whereabouts of a powerful occult book. As other patients start to disappear, Trevor begins to wonder who and where he really is.

About to finish high school, budding inventor Z.T. dreams of escaping both his sleepy town and his gloomy, widowed Dad, Cole. But his ambitions get a stunning reality check with the arrival of Zack, a raving, 68 year-old drunk claiming to be the boy's older self. Suspiciously unable to recall the exact details, Zack is desperate to avert a single, tiny mistake he claims sent the rest of his years into a tragic spiral. As the two forge a shaky alliance to piece together the old man's fragile memory, Z.T. deals with the pressure from his well-meaning Coach and courts a new love, Delena. After a devastating confession from Z.T.'s father, Zack's visit takes on new gravity. Now one man, split in two by fifty lost years, risks everything to save his future and his past in a perilous race Against Time.