Cozy, a dissatisfied housewife, meets Lee at a bar. A drink turns into a home break-in, and a gunshot sends them on the run together, thinking they've committed murder.

In Los Angeles, a colorful assortment of bohemians try to make sense of their intersecting lives. The moody Dark Smith, his bisexual girlfriend, her lesbian lover and their shy gay friend plan on attending the wildest party of the year. But they'll only make it if they can survive the drug trips, suicides, trysts, mutilations and alien abductions that occur as one surreal day unfolds.

Paris 2052. Julia, 80 years old, had a fulfilled life. On her birthday, she reflects on the decisions and circumstances that could have led her on different paths. From the age of 17 to this day, her life was full of small but critical moments. Each was a turning point with dramatic consequences. What would have happened if she had forgotten her passport, chosen a different line at the store, driven the scooter this one time...? Is her life a succession of coincidences and accidents or a ready-made path?

In the midst of the AIDS crisis, a young man from the suburbs moves to the big city of New York and ends up working as a hustler.

Johnny Truelove likes to see himself as tough. He's the son of an underworld figure and a drug dealer. Johnny also likes to get tough when things don't go his way. When Jake Mazursky fails to pay up for Johnny, things get worse for the Mazursky family, as Johnny and his 'gang' kidnap Jake's 15 year old brother and hold him hostage.

In Providence's Italian neighborhood, Federal Hill, five young are immersed in drugs, crime and violence. Everything changes when one of the guys in the band know love.

A man makes a bet in Las Vegas with some men who want to kill him. He bets he can stay alive for 24 hours, then comes to Cleveland to elude them.

Charlie returns to his old town where he meets his ex-girlfriend again and tries to get her back.

A cul-de-sac in an oppressive suburb becomes a literal dead end for wife and mother Karen Christianson when she is brutally murdered in her own home. In the wake of the event, Karen's teenage daughter Ellie begins to exhibit bizarre behaviors as she slowly acquires her mother's demeanor and mannerisms. Meanwhile, Karen's husband Ben nurtures a less-than-innocent interest in the family's sultry live-in nanny, Lena.

Victor is a cook who works in a greasy roadside restaurant owned by his mother, Dolly. It's just the two of them, a waitress named Delores, and a heavy drinking regular, Leo. But things change when Callie, a beautiful college dropout, shows up as a new waitress and steals Victor's heart. But Victor is too shy to do anything about it, and too self-consciously overweight to dream of winning Callie away.