A UFC Middleweight Championship rematch between current champion Alex Pereira (also former Glory Middleweight and Light Heavyweight Champion) and former champion Israel Adesanya is expected to headline the event. The pairing previously met at UFC 281 in which Pereira captured the title by fifth round knockout. The two also previously met twice in kickboxing matchups. The first in April 2016 which Pereira won by unanimous decision. Their second meeting took place at Glory of Heroes 7 in March 2017 which Pereira won by third round knockout.

UFC 269: Oliveira vs. Poirier was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on December 11, 2021, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States. A UFC Lightweight Championship bout between current champion Charles Oliveira and former interim champion Dustin Poirier served as the event headliner.

UFC Fight Night 51: Bigfoot vs. Arlovski was a mixed martial arts event held on September 13, 2014 at Ginásio Nilson Nelson in Brasília, Brazil. The event was headlined by a heavyweight rematch between Antônio Silva and Andrei Arlovski. Their first fight at Strikeforce: Heavy Artillery ended in a unanimous decision victory for Silva.

UFC Fight Night 206: Holm vs. Vieira was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on May 21, 2022, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A bantamweight bout between former UFC Women's Bantamweight Champion Holly Holm and Ketlen Vieira headlined the event.

UFC 282: Błachowicz vs. Ankalaev was a mixed martial arts event produced by the Ultimate Fighting Championship. It took place on December 10, 2022, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States.

UFC on ESPN 59: Namajunas vs. Cortez was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on July 13, 2024, at the Ball Arena in Denver, Colorado, United States. A women's flyweight bout between former two-time UFC Women's Strawweight Champion Rose Namajunas and Tracy Cortez headlined the event.

UFC Fight Night 113: Nelson vs. Ponzinibbio was a mixed martial arts event produced by the Ultimate Fighting Championship held on July 16, 2017 at The SSE Hydro in Glasgow, Scotland. A welterweight bout between Gunnar Nelson and Santiago Ponzinibbio headlined the event.

UFC on Fox 26: Lawler vs. dos Anjos was a mixed martial arts event produced by the Ultimate Fighting Championship held on December 16, 2017, at the Bell MTS Place in Winnipeg, Manitoba, Canada. The event was headlined by a welterweight bout between former UFC Welterweight Champion Robbie Lawler and former UFC Lightweight Champion Rafael dos Anjos. On October 13, UFC President Dana White announced that the winner of the main event would receive a title shot against current champion Tyron Woodley, who won the belt by defeating Lawler by first-round knockout at UFC 201.

UFC Fight Night 140: Magny vs. Ponzinibbio was a mixed martial arts event produced by the Ultimate Fighting Championship that was held on November 17, 2018 at Estadio Mary Terán de Weiss in Buenos Aires, Argentina. A welterweight bout between Neil Magny and Santiago Ponzinibbio headlined the event.

UFC Fight Night 70: Machida vs. Romero was a mixed martial arts event held on June 27, 2015, at the Seminole Hard Rock Hotel and Casino in Hollywood, Florida. The event was headlined by a middleweight bout between former UFC Light Heavyweight champion Lyoto Machida and 2000 Summer Olympics silver medalist in freestyle wrestling Yoel Romero.