Hendro, Diana’s father, does not approve of her romance with Bije, and wants to marry Tony. Then Diana runs away with Bije to a small village where Diana’s aunt lives. This infuriates Hendro and he orders his men to capture Bije. Eventually, Bije and Diana return. When Diana is at home, she feels pain in her abdomen, and she is diagnosed of having a malignant cancer in her ulcer and won’t live long. Hendro even apologises to Bije’s father, but the latter refuses him. Bije even begs to his father to apologise to Hendro, but instead, Bije is thrown out of the house. Eventually Bije and Diana get married, but before the honeymoon ends, Diana passes away on Bije’s lap.

Rafli, Atika, and Saskia are three friends struggling to develop a music career in Jakarta. They later find a producer who manages to make them famous. Rafli and Atika are also involved in a love relationship. Meanwhile, Saskia, who is in love with Rafli, feels left out. So she decides to leave the group and tries to struggle as a soloist. In her frustration, Saskia gives her love to Eros, a drug addict, who sells Saskia to wealthy men. Saskia also becomes a drug addict. Learning of Saskia’s fate, Rafli and Atika are devastated. Atika gives up Rafli to love and look after Saskia. Rafli accepts Atika’s decision, even though it is also a major sacrifice for Atika.

The movie follows two castaway children who grow up with one of their fathers, but must fend for themselves after they are captured and deified by natives. Adapted from Henry De Vere Stacpoole's novel The Blue Lagoon, via the film of the same name, Pengantin Pantai Biru introduces several differences to the story.