Working-class father John Crowley is finally on the fast track to corporate success when his two young children are diagnosed with Pompe disease—a condition that prevents the body from breaking down sugar. With the support of his wife, John ditches his career and teams with unconventional specialist, Dr. Robert Stonehill to found a bio-tech company and develop a cure in time to save the lives of his children. As Dr. Stonehill works tirelessly to prove the theories that made him the black sheep of the medical community, a powerful bond is forged between the two unlikely allies.

Eva, who vows to live without regrets following the death of her best friend, Liz. The two girls had alter egos, Vicky and Veronica, and would imagine doing highly questionable things that they would never do in real life that they compiled into The Never List, which Eva vows to complete.