A psychiatric hospital is turned upside down when a mysterious drifter is admitted and assigned to room 316. Known only as John Doe, the other patients believe that he bears an uncanny resemblance to Jesus Christ.

On the eve of the Apocalypse, a motley group of strangers plays Russian Roulette with a man claiming to be the Devil for a chance to save the world.

When Alana, a naïve stripper, is raped by her boss, Stag, and his drug dealer friend, she turns to her fellow dancers for help. Joined by the beautiful Roxy and seductive Crystal, they hatch a plan to kidnap Stag and force him to give them the combination to his safe. Using his own vices against him, they seduce and drug him. When he wakes he is cuffed in his office where three women he has wronged in different ways hold him captive. In what becomes a grim battle of wills, the girls use physical and mental torture to try to force the combination from him, needing the money to flee before he gets free and kills them all. But they quickly realize they're in over their heads as everything that can go wrong does. As the walls close in around them they have until dawn to get even, get the money and get gone.

What starts as just another delivery becomes the catalyst for life-shattering trouble. With Brian injured and evidence mounting against them, three friends find themselves on the run from the law. In a panic, Brian turns to his mentor and ringleader, Bear, and together they come up with a perfect scheme of betrayal and murder.

The past catches up to three exotic dancers, two of whom were involved in the famous Wisconsin strip club massacre.

A top secret Alaskan lab goes dark due to an unexplained incident, prompting the military to send a black ops team to recover sensitive data and destroy the lab, only to find their ranks infected with a deadly alien virus.