ER doctor Tsuyoshi Matsuoka receives a patient with a virus unlike anything he's seen before. His symptoms include high fever, convulsions, vomiting of blood and multiple organ failure. Could this be a new form of influenza or is it some other variety of virus? As the situation worsens and more cases begin arriving, a medical officer from the World Health Organization named Eiko Kobayashi is dispatched to the area. At the rate the virus is spreading, the entire city’s transportation system and infrastructure would be brought to a halt within 3 months. Within 6 months it could spread to tens of millions of people--reaching a death toll far worse than any war.

A samurai from the Edo Period time travels to present day Japan where he meets a divorcee and her son. Soon, he discovers a passion for making pastries.