Buenos Aires movie director, very fond of the legend of the King of Patagonia and Araucania, decides to make a movie about it. Despite of financial troubles, technical problems, misfortune and desertions, he undertakes the journey to Patagonia for the film with a second-rate actor company. Neglected by the producer and shortly after by the company, he will make the movie alone, in a surreal landscape like mad.

Traveling dentist O'Connell traverses South America on his motorcycle for the 'Eversmile' foundation of New Jersey, in a fight not only against cavities, but also against fear, ignorance, indifference - and established antediluvian dentists. During a stop at a lonesome garage he meets Estella, who is supposed to marry a few days later. However she'd rather come with him - to meet a former boyfriend in another town, she says. Expecting problems, he refuses to take her, but she tricks him into it and then tries hard to convince him of her qualities and let her stay with him.

Manuel is a lonely young man of upper middle class who lives in Buenos Aires with his mother. Due to a fortuitous circumstance, one day he discovers that his father, whom he does not know and whom he supposes living abroad, is in the country. He decides to go and look for him and on his motorcycle starts a long way south through Patagonia.