Continuing the tradition of national artist Ishmael Bernal's benchmark film Working Girls after 25 years, Working Girls of 2010 depicts the role of women in the new millennium. Seven women of different backgrounds, stories and personalities entwined in a colorful story of family, love and life.

Ricardo is a punctilious son who dutifully helps out with his impoverished family’s needs. But the town of Alitagtag isn’t a solicitous environment for a young strapping lad like this baby faced protagonist. His lazy, unemployed father is a vicious gambler who wagers on money he doesn’t have. With debts piling up, Ricardo’s father is soon dodging equally miscreant collectors and the people he owe money to. One day, during an altercation with his wife (she refuses to hand him her savings allotted for paying bills), he accidentally stabs her dead. He makes a run from the crime scene. Ricardo comes home and finds his mother (Beth Coronel) slain. While attempting to remove the knife from his mother’s chest, a neighbor enters the scene screaming, “Bakit mo pinatay ang nanay mo?” This time, it was Ricardo’s turn for a hasty skedaddle. Meanwhile, the runaway father gets runover by a speeding truck. And there goes the solitary witness of Ricardo’s innocence.