Perennial university student Eva, who is still having difficulties at adjusting to big city life, takes up a job as dog sitter. After visiting the owner, she finds out the dog—Spotty—is actually Matteo, an introverted young man who copes with modern life by dressing up as a giant puppy.

The marriage of an actor and a freelance film editor breaks up unexpectedly in front of two filmmakers' camera.

After a fateful encounter in the summer of 1966, the lifepaths of two brothers from a middle-class Roman family diverge, intersecting with some of the most significant events of postwar Italian history in the following decades.

Four physically disabled lowlifes plot the perfect heist, but things go south when each reveals an agenda of their own.