The Australian Opera Chorus & The Elizabethan Sydney Orchestra, Richard Bonynge Lucrezia Borgia, infamous noblewoman of the Renaissance, has outlived three husbands and is now married to Don Alfonso, Duke of Ferrara. After the Borgia’s palace is defaced by vandals, Lucrezia demands the desecrator’s death to avenge the insult. When the noble young soldier Gennaro is arrested for the crime, Lucrezia’s thirst for vengeance and murder sets in motion a tragic chain of events that eventually destroys her enemies and herself.

Donizetti wrote Lucia di Lammermoor in 1835, when he was reaching the peak of his reputation as an opera composer. Gioachino Rossini had recently retired and Vincenzo Bellini had died shortly before the premiere of Lucia leaving Donizetti as "the sole reigning genius of Italian opera". Not only were conditions ripe for Donizetti's success as a composer, but there was also a widespread interest in the history and culture of Scotland. The perceived romance of its violent wars and feuds, as well as its folklore and mythology, intrigued 19th century readers and audiences. Walter Scott dramatized these elements in his novel The Bride of Lammermoor, which inspired several musical works including Lucia.