After accepting temporary work in a laboratory Cesar begins to notice strange events related to the treatment of a patient with the number 27, this disturbs him the extent of causing insomnia and hallucinations. Isela and Marcos, his coworkers attribute this to the Cesar fatigue, however the real reason for these views is more real and dangerous than they think.

Mia, an expert speaker in witchcraft, takes a trip to see a therapist. On the way she meets a group of young people who will begin to die one by one to bring an evil spirit back from death.