A circle of thirty-something friends reunite for a weekend away to celebrate the same sex wedding of a member of their group. Yet, despite their best efforts to behave themselves, a series of surprise plans, unexpected arrivals and exposed secrets lead to an explosion of drama that, coupled with the flammable combination of hurt feelings, unresolved tensions, and lots of wine cannot be contained.

Ever since her father drilled into her head that monogamy isn't realistic, magazine writer Amy has made promiscuity her credo. As much as she enjoys an uninhibited life free of commitment, Amy is really in a rut. While writing a profile about charming and successful sports doctor Aaron Conners, she finds herself actually falling in love for the first time -- and what's more, Aaron seems to really like her too. Amy starts to wonder if it's time to clean up her act and face her fears.

Lou, a former professional golfer, turned motivational speaker, seems to have it all: fame, money, and a beautiful live-in girlfriend, Alex. Her seemingly perfect life is turned upside down when she is attacked near her home in Manhattan.