After the death in suspicious circumstances of Charles Baskerville, the last descendant of the lineage of the Baskervilles, Henry, returned to the old family mansion. The charismatic detective Sherlock Holmes and his faithful assistant, Dr. Watson, investigating the case, and discover the existence of a supernatural hound that in addition murderer according to history, killed many years ago Hugo Baskerville, the first of the line, and it seems that the curse stalks his descendants.

In Canada a man investigates his brother's death and saves a suspected girl from kidnap.

Holmes finds that the disappearance of respectable middle class Neville St. Clair may be linked to a filthy beggar living above an opium den.

A girl detective and a reporter recover stolen gems hidden in a Chinese idol.

An Earl's disowned son becomes a chauffeur, loves a landlady, and is jailed for theft.

An adaptation of a Sherlock Holmes short story starring Eille Norwood.

In Edinburgh a foundry owner weds a German spy's widow who becomes a nurse.