Two weeks after the events in "Terror at Black Tree Forest" young Mare Strode returns home from Falls City Memorial Hospital. She brutally murders her mother and "escapes" back to Black Tree Forest. There, she dons the original psycho's outfit and continues the cycle of murder with a whole new group of adventure-seeking teens.

When the drug deal goes bad and Jason disappears, Nikki is trapped on an upper floor of the warehouse with a vicious ex-military enforcer, a gunshot victim, a violent addict and his three hostages. All the exits have been blocked and somewhere in the darkness is something with a taste for blood and a love of pain.