The story is set in the British province of New York during the French and Indian War, and concerns—in part—a Huron massacre (with passive French acquiescence) of between 500 to 1,500 Anglo-American troops, who had honorably surrendered at Fort William Henry, plus some women and servants; the kidnapping of two sisters, daughters of the British commander; and their rescue by the last Mohicans.

Richard Dix as Dan Taylor and Preston S. Foster as Paxton Bryce are two longtime friends seeking their fortune in Texas after the war. The two men decide, not without problems, to establish a cattle empire. Paxton becoming too ambitious, distances himself from Dan and Abby, Paxton's wife. It will only be after a personal tragedy that he will come back to his senses.

A con man heading west to search for gold teams up with a pair of scheming brothers along the way. The trio soon find themselves in the middle of a feud between two rival families and two underhanded land developers.

While Charlie is distracted with the birth of his first grandchild, son Jimmy impersonates his father in order to investigate a murder aboard a freighter in the harbor.

Sheriff Holt is determined to prove that prisoners can be rehabilitated and released into society in this prison drama. In charge of a new kind of program, the sheriff places inmates in a clean environment and makes them build a road. Despite the improved conditions, the criminals continue to pull off a few shady shenanigans as an innocent man who is sent there soon discovers.

A young woman uses her body and her sexuality to help her climb the social ladder, but soon begins to wonder if her new status will ever bring her happiness.

Steve Grey, reporter for the Daily Star, has a habit of scooping all the other papers in town. When Henry Mander is investigated for the murder of his shady business partner, Grey is one step ahead of the police to the extent that he often dictates his story in advance of its actual occurrence. He leads the police through an 'open and shut' case resulting in Mander being tried, convicted and sentenced to death. Columnist Mary Shannon is in love with Steve but she sees him struggle greatly with his last story before Mander's execution. When she starts typing out the story from his recorded dictation, she realizes why.

While on a ship to Skagway, Alaska, Duke and Chester find a map to a secret gold mine, which had been 'stolen' by thugs. In Alaska to recover her father's map, Sal Van Hoyden falls in with Ace Larson, who secretly wants to steal the gold mine for himself. Duke, Chester, the thugs, Ace and his henchman chase each other all over the countryside—for the map.

A number of swamp land men have died by strangulation and the inhabitants believe that an innocent man they hanged is seeking revenge on all of the male descendants of those responsible for his death. Maria, granddaughter of the innocent ferryman, decides to operate the ferry service. Chris Sanders, a son of one of the men who did the hanging, and Maria fall in love. The "strangler" seizes Chris and Maria offers her life if Chris is spared.

A playwright descended from the Borgia family becomes a murder suspect.