As they enter their third year of medical school, a group of young students must prepare to decide what they intend to specialize in. Somehow, they must impress the Chief of Surgery while learning how to survive the life-and-death area of medicine and the complexity of their everyday lives.

After a family tragedy in the chaotic city, Chris and Maggie Conley, in a last-ditch effort to save their dying marriage, purchase an isolated home in the deepest woods, to which they quickly discover evil has a key.