XENOA 2 : Clash of the Bloods is the story of Clyde who suddenly discovers his power, being the son of Drix, one of the three Royal siblings from the planet Xenoa. The other siblings- Eli and Zeus learned that Clyde started to act strange and unfortunate things are happening around. This aroused the suspicion of the local police and they started an investigation, headed by Chief Vondeux.

A Filipino worker is on the death row for killing his employer. Because of a lady reporter who is bent on doing a full story about him, government officials are now trying to help him. But Fidel insisted that he killed his employer on purpose. Vega learned about his past- a boy-next-door type of person who grew up with a loving family. His profile doesn't fit the picture of a killer. Sister Lourdes, the Filipino nun who visits Fidel regularly wants to know the truth too.