A group of high school girls discover the truth to an urban legend when one by one, each begins to die under mysterious circumstances.

Yumiko has been invited by her cousin to spend summer vacation in a rural village. Once they arrive, she is mad to feel very unwelcome by the mysterious locals who keep referring to her as "Snake Girl."

Kageko, a teacher in a small mountain village with a thriving Japanese paper industry, is visited by a former student, who proposes a plan to manufacture counterfeit money. She initially refuses, but eventually decides to join the project for the sake of the poor children in the village and her own mentally handicapped child.

Osanai Kei enjoys a peaceful and happy life with his wife Osanai Kozue and daughter Osanai Ruri, but his wife and daughter die in an accident. Osanai Kei's life suddenly changes. One day, a man named Misumi Akihiko visits Osanai Kei. Misumi Akihiko tells him that on the day Osanai Kozue and Osanai Ruri died, Osanai Ruri, who was a complete stranger to him, was coming to see him. Misumi Akihiko tells him about a woman named Masaki Ruri, who he once loved. These people, who don't seem related, connect under the name of love.

Shuichi Furukawa receives a phone call from his mother. She reminds him that they are moving the next day. The following day, Shuichi takes a train ride back to his hometown. He arrives at his parents home, but nobody is home. He looks for the house key under a potted plant but can't find the key. He starts to thinks back to his childhood days in his parents home. Shuichi grew up with his younger brother, older sister, father who ran a shoe making business out of their garage and mother. Shuichi grew up with a crush on an older woman who lived next door and he loved to make piggy banks out of empty whiskey bottles. One day on a school picnic, Shuichi's classmates grabbed a lunchbox from a fellow student and eventually gave the lunch box to Shuichi. All the other students chanted "throw it away," while Shuichi's former friend looked on in despair.

A novice red blood cell and a relentless white blood cell work together to protect their human from invading germs, pathogens and other threats.