Young hot travelers are sidelined by a road blocked with fallen trees, and stop for a night at the mansion belonging to sexy Sebastian. The house has a history of voodoo, mayhem and horror, and new arrivals are fresh meat for the hungry house...

Carrie, Charlotte, and Miranda are all married now, but they're still up for a little fun in the sun. When Samantha gets the chance to visit one of the most extravagant vacation destinations on the planet and offers to bring them all along, they surmise that a women-only retreat may be the perfect excuse to eschew their responsibilities and remember what life was like before they decided to settle down.