The charismatic Snaporaz encounters an alluring woman on a train and pursues her through a forest. He ends up at a hotel populated by women gathered for a feminist conference, where he is an unwanted presence. Snaporaz soon discovers he’s entered a phantasmagoric world where women have taken power.

Now an agent of Interpol undercover, the former Inspector Giraldi, goes to New York to find his friend Salvatore Esposito, aspiring restaurateur in Little Italy, suffocated by debts with the usurers headed by Don Gerolamo. He will remove the gang and assure her of justice, but she will suffer the advances of the Boss's daughter, the ugly Maria Sole.

Based on the memoirs of author Curzio Malaparte, diplomatic liaison between the Allied and Italian forces after the defeat of the Nazis in Italy, The Skin follows the collapse of Italian society under the US occupation and the desperate measures required for survival.