Vincent Lubeck is a vicious ex-convict. His criminal activities are despised by his family, but he uses and abuses them in the course of his crimes. Eventually his own brother must stand up to him.

In a shadowy world stitched from nightmares, a young woman's harrowing journey in a seedy hotel unveils her traumatic past. Haunted by violence and stalked through desolate streets, her psyche unravels as she confronts an abusive husband and unsettling memories.

Advertising executive Alan Miller, a recovered alcoholic who now does interventions on behalf of Alcoholics Anonymous, is called to help Broadway actress Jenny Carey whose developing career is threatened by an increasing dependence on alcohol. Alan's growing interest in Jenny strains his marriage to Edna, with whom he has two children.

Homer Flagg is a railroad worker in the small New Mexico town of Desert Hole. One day, he finds an abandoned automobile at an old atomic proving ground. His doctor and best friend, Steve Harris, diagnoses him with radiation poisoning and gives Homer three weeks to live. A big city reporter hears of Homer's plight and convinces her editor to provide an all-expenses paid trip to New York.