Trying to recover from the nearly marriage-breaking stress following the death of their child, Jack and Stephanie spontaneously take off on a road trip. But when their car breaks down in a remote area, they find themselves in a horrific nightmare. Seeking shelter in a house, they soon realize that more danger lurks inside than outside in this spine-chiller based on Ted Dekker and Frank Peretti's best-seller.

The film follows three young men as they are drawn into lives of crime. Nick (Crowley) uses his entry-level corporate job to commit credit card fraud and deals drugs on the side. K-Luv (Mackie) is a member of the "V-Dubs", an African-American street gang. Lincoln (Leung) is a rising figure in the Chinese mafia. Gentrification forces Nick's family to move out of their home in the Mission District into Hunter's Point where they are harassed by the V-Dubs. K-Luv's side business of selling bootleg compact discs leads him to enlist Nick's help to bootleg CDs and to negotiate a truce with Lincoln. Lincoln conducts an affair with his boss' daughter Angela (Carpio), a Stanford student engaged to a medical student classmate.

A woman undergoes an illegal organ transplant only to discover that the young girl who donated the kidney died during the operation. Determined to stop this heinous activity, but torn by the moral dilemma of being saved by it, she fights against her reluctant husband, an LAPD Detective, to pull down the ring of criminals behind it.

Fired from his job, a former executive turns to impregnating wealthy lesbians for profit.