Some of Sin City's most hard-boiled citizens cross paths with a few of its more reviled inhabitants.

Seattle medical examiner David Krane is obsessed with solving his wife's murder. A possible solution presents itself in an experimental "memory" serum designed by a neurobiology professor, which has the ability to transfer memories from one person to another, but with potentially fatal consequences.

Freddy Heflin is the sheriff of a place everyone calls “Cop Land” — a small and seemingly peaceful town populated by the big city police officers he’s long admired. Yet something ugly is taking place behind the town’s peaceful facade. And when Freddy uncovers a massive, deadly conspiracy among these local residents, he is forced to take action and make a dangerous choice between protecting his idols and upholding the law.

The true story of Henry Hill, a half-Irish, half-Sicilian Brooklyn kid who is adopted by neighbourhood gangsters at an early age and climbs the ranks of a Mafia family under the guidance of Jimmy Conway.

A man named Farmer sets out to rescue his kidnapped wife and avenge the death of his son – two acts committed by the Krugs, a race of animal-warriors who are controlled by the evil Gallian.

A beautiful artist helps an amnesiac piece together his identity and evade a gangster on his trail.

A successful artist looks back with loving memories on the summer of his defining year, 1974. A talented but troubled 18-year-old aspiring artist befriends a brilliant elderly alcoholic painter who has turned his back on not only art but life. The two form what appears to be at first a tenuous relationship. The kid wants to learn all the secrets the master has locked away inside his head and heart. Time has not been kind to the old master. His life appears pointless to him until the kid rekindles his interest in his work and ultimately gives him the will to live. Together, they give one another a priceless gift. The kid learns to see the world through the master's eyes. And the master learns to see life through the eyes of innocence again. This story is based on a real life experience.

Ray Kinsella is an Iowa farmer who hears a mysterious voice telling him to turn his cornfield into a baseball diamond. He does, but the voice's directions don't stop -- even after the spirits of deceased ballplayers turn up to play.

Complete strangers stranded at a remote desert motel during a raging storm soon find themselves the target of a deranged murderer. As their numbers thin out, the travelers begin to turn on each other, as each tries to figure out who the killer is.

A boy named George Jung grows up in a struggling family in the 1950's. His mother nags at her husband as he is trying to make a living for the family. It is finally revealed that George's father cannot make a living and the family goes bankrupt. George does not want the same thing to happen to him, and his friend Tuna, in the 1960's, suggests that he deal marijuana. He is a big hit in California in the 1960's, yet he goes to jail, where he finds out about the wonders of cocaine. As a result, when released, he gets rich by bringing cocaine to America. However, he soon pays the price.