As 4/20 begins, a dispensary owner launches into a day of haphazard activities he hopes will spark new business and keep his struggling store afloat. His biggest threat is a wide-eyed drug dealer hoping to reclaim the local cannabis business. Meanwhile, a trio of soon-to-be high school graduates try to scheme their way in to buy enough weed to properly toast their long-lasting friendship. And as two potential lovers struggle to align their views on pot, an elderly woman strikes up an odd friendship with a young immigrant with a secret. All the while, an edibles chef strives to impress her disapproving family with her burgeoning food truck. On this glorious holiday, people across life's spectrum will find they have more in common than just a love of herb.

Two strangers stuck in Los Angeles for the night are forced to confront their fears and take control of their lives.