A second take in life, with nun of the regrets.

The story of a young boy in the Midwest is told simultaneously with a tale about a young girl in New York from fifty years ago as they both seek the same mysterious connection.

Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.

A young Russian woman, smuggled into America by human traffickers, and a notorious Egyptian transporter hired to drive her from the Mexican border to New York City, form an unlikely bond that transforms them and threatens to derail the traffickers' plans.