Since the 1960s, a disproportionate number of the population in and around Nome, Alaska, have gone missing. Despite FBI investigations, the disappearances remain a mystery. Dr. Abigail Tyler, a psychologist, may be on the verge of blowing the unsolved cases wide open when, during the course of treating her patients, she finds evidence of alien abductions.

Widower Cedric Brown hires Nanny McPhee to care for his seven rambunctious children, who have chased away all previous nannies. Taunted by Simon and his siblings, Nanny McPhee uses mystical powers to instill discipline. And when the children's great-aunt and benefactor, Lady Adelaide Stitch, threatens to separate the kids, the family pulls together under the guidance of Nanny McPhee.

When Lenore Harker learns that she's pregnant, she leaves graduate school to set up a home with her boyfriend Frank in the country. The happy new family's lives takes a gruesome turn when animals and people end up brutally dead – all with a mysterious connection to their newborn.