A man, after being robbed and shot fourteen years earlier, succumbs to a life of addiction and ultimately loses the love of his life and knowing his only child. After meeting a local pastor, Brian is forced to confront his alcohol addiction. His volunteer work at the pastor's church leads him to a job as a home health-care worker. Upon meeting his first patient, Taj, the two men are unaware that their lives will forever be changed through this trying relationship.

Desperate for a breakthrough as she nears the big 4-0, struggling New York City playwright Radha finds inspiration by reinventing herself as a rapper.

Rosalina comes back after her music cruise, but Michel (the French guy Rosalina kissed on the cruise) also comes back, criticizes Nat's music, and kisses Rosalina which Nat sees. This causes a heated fight between Nat and Rosalina in which they break up and Rosalina quits the band.

The Naked Brothers Band and another band, the L.A. Surfers, find themselves competing in a "Battle of the Bands" charity event benefiting Little Kids Rock. Rosalina starts to fall for the L.A. Surfers' lead singer, Bobby Love. It annoys Nat that Rosalina hangs out with the opponent's lead singer. It turns out that Bobby is just dating Rosalina to get to Nat and is lying about everything, i.e, his British accent, not writing his own songs, etc. Nat and Bobby fight and declare at a press conference that the charity event is now a competition and the losing band's proceeds from their next CD goes to the charity.

The band's next concert stop is in New Orleans where Nat reunites with a childhood friend, sending Rosalina into a jealous frenzy! Meanwhile, Alex initiates an extreme environmental movement to help save polar bears at the North Pole, but devious reporters frame him to appear as a conceited rock star who hates Santa!