Deadly Girls Night Out is the story of three close friends planning a party out for the night. However, the night ends up in a tragic death that unravel deep secrets.

A small team of scientists must race against time to stop what seems to be a cascade of global disasters signaling the possible apocalypse and end of days.

While on a road trip through the desert, Charlie and her boyfriend Aidan break down in the middle of nowhere. While Aidan waits for a tow truck, Charlie heads to a nearby diner to find help. When Aidan goes missing, Charlie finds herself stranded in a strange town unsure who to trust. The only thing she knows is she might just be their only chance to get out alive.

An alien spacecraft lands near New York and destroys everything as it heads toward Washington D.C. If it reaches the capital, it will trigger an invasion. Scientists and the military must stop it before it's too late.

In a city where social workers play a larger role in assisting the mentally ill in the countryside, a social worker and an infamous police officer must resolve their differences and work as a team to survive the night.