After hitting dead ends in life, Jyothi, an Indian housewife, and Sophie, a stoner musician, find themselves on the run from the law, together on a wild, surreal American road trip from Durham, North Carolina to Montreal, Canada.

Struggling with new parenthood and stalling careers, Kallia and Ram's lives are thrown into chaos when Kallia's blind mother goes on a mission to exorcize the family from the evil eye.