Feckless aspiring architect Stéphane leaves his pregnant girlfriend for theater designer Sabine; Sabine in turn vainly attempts to overcome her violent obsession with an actor in her theater company. A game of emotional chutes and ladders ensues.

In the 18th Arrondissement of Paris, Lambert, an aloof garage manager working the night shift at a petrol station spends his time drinking on the job, content in his own company. One night, Bensoussan, a small-time drug pusher in dire straits falls in on a stolen moped pretending to need a spark plug. The two men develop an unlikely friendship.

The name of painter Jean-Honore Fragonard (1732-1806) is synonymous for a kind of painting style which celebrates carefree romantic life, indoors and out. He was a painter during the final decades of the French monarchy. In this story, he and his brother Cyprien (Robin Renucci), who is an early pioneer in medical anatomy (he dissected corpses and made drawings of what he found in them), have fallen in love with the same woman, Marianne (Philippine Leroy-Beaulieu), a laundress. This attraction has not escaped the notice of Salmon d'Anglas (Sami Frey), a conniving nobleman, who has his heart set on getting revenge on Jean-Honore (Joachim de Almeida) for refusing his patronage and becoming the darling of the French court.