Samuel est psychanalyste. Toute la journée, il voit des patients exprimer des griefs, en particulier des adolescents rebelles qui méprisent leurs parents. Cette situation l'a conduit à voir d'un mauvais œil l'idée de sa paternité. C'est alors que sa compagne Mathilde lui annonce qu'elle est enceinte. Terrifié par l'idée, Samuel vit les neuf mois de grossesse de Mathilde plutôt comme un cauchemar, et les conseils de son ami Marc, homme à femmes mais célibataire endurci, n'arrangent rien à son angoisse. De leur côté, Georges et Dominique, la sœur de Marc, déjà parents de trois filles, affrontent sans inquiétude la quatrième grossesse de Dominique. L'expérience des uns va finalement avoir raison des appréhensions des autres, et entre les deux couples vont se tisser de solides nœuds d'amitié.

JAM (Christian Clavier), a French "master of the universe" is on the brink of a major takeover when he starts suffering from anxiety attacks. His doctor (Lhermite) thinks it is to do with childhood experiences and suggests he searches back in his mind to something that could be the trigger and will prove to be the antidote.

When Frank is diagnosed with depression, his friends try to cheer him up -- and it quickly becomes clear that they're just as down and out as he is.

40-something Victor, humanities professor and amateur meteorologist, is a madcap, a friendly dabbler, who lives day by day, alongside is wife Anne.

The journey strewn with adventures of François Veber, electrician who decides to embark on the theater. For his passion, he leaves his wife. Particularly awkward, he will have to work to achieve his dream.

Gaëtan (age 70) pees in dots and dashes. Max (age 50) can no longer get hard. Félix (age 20) shoots too soon. 3 men, 3 generations, 1 thing in common: manhood malfunctions.

Julien, an honest policeman, is asked to infiltrate a terrorist organization. He soon meets the charming Brigitte. But soon, manipulated by his superior, Julien finds himself involved in a dangerous affair: a gigantic campaign of intoxication.