"Mad in Italy" is a truly disturbing psychological film based on true events about one girl's ordeal to stay alive at the hands of a young maniac. Featuring amazing cinematography by one of the most talented Italian directors of photography Mirco Sgarzi (House of Flesh Mannequins and Orgy of Blood).

1275 a.C. - A young girl is imprisoned in the dungeons of an abbey where an alchemist uses her for his strange experiments. Only a young amanuensis will try to free her at any cost. 2011 a.C. - A couple of young teenagers, Cris and Jessy, go missing in the woods while a young woman comes out from the middle of nowhere. During the first investigations, the police find an odd manuscript from a tomb. Today - Leonardo, the Chief inspector of the Police department, is in charge of the investigation of the two teenagers disappearance. He's compelled to leave his video-testimony, because in the light of his last findings, he fears for his own life.

The son of an indebted restaurant owner joins a foreign girl in search of her sister. Together, they’ll have to fight side by side against the most ruthless members of the Roman criminal underworld.