Aliens land in the mythical town of "Speelburgh, U.S.A" searching for the source of rock & roll. What they find is a gang of teenagers, led by Dee Dee and Frankie, along with Frankie's posse/rock band, the Pack. The leader of the aliens takes a shine to Dee Dee and all sorts of trouble breaks out.

The true story of the US Government's 1932 Tuskeegee Syphilis Experiments, in which a group of black test subjects were allowed to die, despite a cure having been developed.