A drama-documentary film about the fatal effect of poor living conditions on health – the so-called "social inheritance." The principal characters in the film are two fourteen or fifteen-year-old children, Carl and Hanne. Covering a hundred-year period and drawing on case stories recorded by actual hospital staff, the film illustrates a number of variations of "the same old story."

A sequel to "Me and Charley", it starts with Steffen's graduation from a secondary school in Århus (Denmark), where he later that day bumps into Charly and their friendship continues while portraying life in Århus 1979.