How the helpers of Sinterklaas are able to do their tricks and get into every house is one of the magical powers of Sinterklaas' Book. But when the book loses it's power, it becomes impossible to to fulfill their duties on December 5. To prevent that from happening, Piet Diego and his Elite team embark on an adventure. Quite a big adventure, because the only place to recover the much needed powers is a magical source in Myra - the birthplace of Sinterklaas!

On her 13th birthday Katie, a talented young girl, receives a magical amulet. This amulet was on a quest to find the fifth and last witch to complete the order of the star witches. Because in it's incomplete form, the order is unable to protect earth against the evil witch Concuela. While Katie is exploring her new magical powers together with her best friend Roy, Grimbeck, the dandy gatekeeper of the star witches arena, as well as the evil Concuela are desperately trying to find Katie.

In this new installment, Mister Twister faces a major challenge as he has to stand on his own. While continuing to inspire his students with creative teaching methods, he deals with changes both at school and in his personal life. The strict principal keeps him on his toes, and his students never fail to surprise him in their own unique ways. Filled with humor and heartwarming moments, the film shows how Mister Twister, despite the obstacles, always manages to bring out the best in his class.