Invicta FC 46 took place Wednesday, March 9, 2022 with 5 fights at Memorial Hall in Kansas City, Kansas.

Invicta FC Phoenix Tournament: Atomweight was a mixed martial arts event that featured an atomweight tournament including 8 fighters vying for a shot at the atomweight championship. The tournament participants were announced to include recent title challenger Jéssica Delboni, Lindsey VanZandt, Jillian Decoursey, Linda Mihalec, Katie Saull, Paulina Granados, Tabatha Watkins, and Katie Perez. Four days before the event, Katie Saull was forced out of the tournament due to travel restrictions and was replaced by Marisa Messer-Belenchia. Like previous Phoenix Tournament events, the first two rounds will be one-round exhibitions, while only the final will be a full three round fight that counts towards the fighter's record.