A large family gathers in the country side for their very elderly grannies' birthday. One gift happens to be from their ostracized, black sheep nephew, and upon opening it, the two loveable grannies turn into rabid, flesh-eating monsters.

The Inquisition is in full swing in 16th century Flanders. Wanted for his dissident writings, the alchemist doctor Zeno has been wandering Europe under an assumed name for twenty years. But he remains a non-conformist. He returns to his native Bruges, where he thinks he has been forgotten. In this silent labyrinth where the faces of the past resurface, he rediscovers his identity and thus signs his death warrant.