The "pasamanos" are a group of young people who transport backpacks with illegal contents from the capital to the suburbs of Buenos Aires. Paula is a "pasamanos" but she is reluctant to let her brother follow in her footsteps.

Olga, Teresa and Pilar have been friends since they were born. For years they vacationed together with their parents, and later together on their own. A few years ago, Teresa got married, and for some years they didn't see each other as much. Teresa's divorce prompts a reunion, so the three of them rent a small house for the weekend. In their first day together, it becomes obvious that everything they share is in their past. They have grown apart.

The story of Maxi Herneston, whose life is far from perfect: he works as an employee in a local video store; he has an older brother who tortures him day and night and a mother obsessed with sex. But these circumstances become minor details when he accidentally ingests a virus from outer space that will make him feel incredibly sick and, in the final instance, will force him to defecate five aliens who at first seem friendly but who later turn out to have their own plans regarding the boy and the future of the earth.

After being expelled for a flagrant foul during a match in Primera C (the fourth division in Argentinian football), Patón Bonasiolle, the captain and midfielder from Talleres de Escalada, realizes his career as a footballer has come to an end. At the age of 35, this means the end of a world he has known since he was a child. Together with Ale - his wife - he looks for a fresh new start.