In the Fabulous Thirties, Doc Savage and his five Amazing Adventurers are sucked into the mystery of Doc's father disappearing in the wilds of South America. The maniacal Captain Seas tries to thwart them at every turn as they travel to the country of Hidalgo to investigate Doc's father's death and uncover a vast horde of Incan gold.

Jonathan Drake, while attending his brother's funeral, is shocked to find the head of the deceased is missing. When his brother's skull shows up later in a locked cabinet, Drake realizes an ancient curse placed upon his grandfather by a tribe of South American Jivaro Indians is still in effect and that he himself is the probable next victim.

In the mid-19th century, Senator William J. Tadlock leads a group of settlers overland in a quest to start a new settlement in the Western US. Tadlock is a highly principled and demanding taskmaster who is as hard on himself as he is on those who have joined his wagon train. He clashes with one of the new settlers, Lije Evans, who doesn't quite appreciate Tadlock's ways. Along the way, the families must face death and heartbreak and a sampling of frontier justice when one of them accidentally kills a young Indian boy.

President Grant orders Indian fighter MacKay to negotiate with the Modocs of northern California and southern Oregon. On the way he must escort Nancy Meek to the home of her aunt and uncle. After Modoc renegade Captain Jack engages in ambush and other atrocities, MacKay must fight him one-on-one with guns, knives and fists.

The daughter of a circus owner fights to save her father from a takeover spearheaded by the man she loves.

Escaping death, a Hebrew infant is raised in a royal household to become a prince. Upon discovery of his true heritage, Moses embarks on a personal quest to reclaim his destiny as the leader and liberator of the Hebrew people.

During the War of 1812 against Britain: General Andrew Jackson has only 1,200 men left to defend New Orleans when he learns that a British fleet will arrive with 60 ships and 16,000 men to take the city. In this situation an island near the city becomes strategically important to both parties, but it's inhabited by the last big buccaneer: Jean Lafitte. Although Lafitte never attacks American ships, the governor hates him for selling merchandise without taxes - and is loved by the citizens for the same reason. When the big fight gets nearer, Lafitte is drawn between the fronts. His heart belongs to America, but his people urge him to join the party that's more likely to win.

The weirdest alien of the galaxy pays a visit to Earth... Jerry Lewis is Kreton, a childish alien who, against his teacher's will leaves his planet to visit the Earth, and lands in the backyard of a famous television journalist who doesn't believe in UFOs and aliens. Wanting to study humans but not able to fully understand them, Kreton makes a mess out of it, generating a lot of comic situations.

Frustrated with the lack of opportunities in his hometown, young Jess Harker plans to leave, but sympathetic stagecoach armed guard Race Crim persuades his boss to give Jess the stage driver job.

Coop's an ex-ballplayer is now a peanut vendor, who takes too much of an interest in the game. But he's passed on his craze for baseball to his son, Christie. When his dad gets fired, Chris makes friends with the former team owner's niece (and her boyfriend Pete), and not only gets his dad's job back, but a batboy position for himself. With his dad's help, Christie begins to make a few suggestions here and there. And as a publicity stunt, the team makes him their youngest manager on record. But when Chris gets sick, Coop has to come to the rescue.