Serena Stalin wanted to learn from the best. So she tracked down Butch Harlow, one of the world’s most notorious serial killers, and blackmailed him into teaching her the fine art of murder. Now, as the lessons begin, teacher and bloodthirsty student unleash an unspeakable passion that forces them to kill over and over again, leaving a trail of horribly mutilated victims in their wake...

Tasha runs a strip club which contains a few vampire strippers. She is well aware of the bloodsucker problem as she is one herself. Heather is an all-American girl who applies for a job to pay her way through school. She is hired but it doesn't take long for Tasha to decide that they should suck Heather into their clan. Only a faltering priest named Seamus can save Heather from the horrible prospect of eternal life.

Heather is an exotic dancer who has become a vampire and works at a nightclub named Vamps, managed by her fiancé Seamus, a defrocked priest. They learn that they have made a powerful enemy in Elizabeth, another comely female vampire whose sister was killed by the denizens of Vamps years before. Elizabeth is eager to get revenge against Heather and her fellow vampire strippers, especially since Heather and Seamus could possibly bring about the Prophesy of the Redeemer, which would bring an end to vampires once and for all.

A public relations firm is really a front for a devil-worshiping cult that kidnaps young models to sacrifice to the devil. A reporter stumbles onto their operation.