It's Tiffany's twenty-first birthday, and she's having a party with her closest friends. There's lots of drinking and kissing, and as the party progresses, various couples pair off, including Tiffany's boyfriend Drew with someone else. Her closest friend, Beth, hears strange noises from time to time, and finally goes to investigate. Tiffany and Drew follow with a flashlight. What sort of party will this turn out to be, and will Tiffany find true love?

Our story follows Jo, an overweight, impassioned reporter with hopes of becoming a news anchor. She is unsuccessful in her attempts until a revolutionary weight loss program is developed, in which trainers occupy the consciousness of their clients and work out their bodies for them.

When three redneck brothers agree to help a woman save her son from an abusive father, they become targets on the run from an odd cast of characters.