Isabel Moreno crosses the border into the United States, thinking only of making enough money to save her deathly ill mother. In Philadelphia, she finds comfort in her cousin Martin and is embraced by his neighbors, Gloria and Maurice. She is surprised to find a new family far from home, but even more surprised to fall in love with the one man that could put her right back where she started, Christopher Fox, an immigration agent. Faced with an ultimatum, Isabel is forced to question her loyalties and choose between her freedom and the love of her life.

Will's best friend and roommate Belcher, a party bum slacker, returns from the dead as a cocky, mischievous, and perverted ghost. He soon discovers his cousin, Krista, has shacked up and moved in with his best friend, Will. Belcher will do anything and everything to destroy this relationship and get his prank buddy back.