During a high-profile Mafia testimony case in Riverside County, a hired killer checks into a hotel room near the courthouse, while his depressed neighbor contemplates suicide over marital problems.

Set in the future, the story follows a young soldier named Johnny Rico and his exploits in the Mobile Infantry. Rico's military career progresses from recruit to non-commissioned officer and finally to officer against the backdrop of an interstellar war between mankind and an arachnoid species known as "the Bugs."

A group of American Army nurses are captured by the Japanese in April 1942 and spend three years in a prisoner-of-war camp in Bataan. Lt Margaret Ann Jessup, the head army nurse, survives the camp and testifies against the Japanese in front of the United States Congressional subcommittee years later as a colonel.