In 1993, spectators at the last screening of a horror film at a downtown cinema fall one by one into the hands of a sadistic and ruthless killer.

Four friends decide to spend a winter weekend in a rented house in a Uruguayan beach town called Neptunia. Once there, the friends begin to realize that the people are acting strange.

A loser is blackmailed by the police. A hitwoman finds an unlikely partner. Two thieves accidentally get their hands on a futuristic weapon. All of them coincide at a legendary party organized by an eccentric drug trafficker named Pancho and get entangled in an epic battle that goes a lot deeper than they could have imagined.