An outlaw saved by a Mexican girl hunts the holdup partner who shot him in the back.

Jobless sportswriter Eddie Willis is hired by corrupt fight promoter Nick Benko to promote his current protégé, an unknown Argentinian boxer named Toro Moreno. Although Moreno is a hulking giant, his chances for success are hampered by a powder-puff punch and a glass jaw. Exploiting Willis' reputation for integrity and standing in the boxing community, Benko arranges a series of fixed fights that propel the unsophisticated Moreno to #1 contender for the championship. The reigning champ, the sadistic Buddy Brannen, harbors resentment at the publicity Toro has been receiving and vows to viciously punish him in the ring. Eddie must now decide whether or not to tell the naive Toro the truth.

In Prohibition-era Chicago, musicians Joe and Jerry witness a mob hit, and flee the state in an all-female band disguised as Josephine and Daphne, but further complications set in.