Un couple se dirige vers un train en partance pour Venise. Sur le quai, Julien annonce à Marie qu’il part en rejoindre une autre et s’en va, la laissant seule à Paris, enceinte. Bouleversée, Marie se refuse à être victime de cette situation. Elle trouve du réconfort dans son travail auprès de ses deux « cow-boys » de patrons, Jean-Jacques et Jean-Loup, qui dirigent un cinéma du quartier latin spécialisé dans les films classiques américains…

Aglaé, a young factory worker, has only one focus in life: her job at a car crash test site. When she learns that the factory is going to be relocated abroad, she accepts, to everyone's surprise, to go to India in order to hold on to her job. Accompanied by two colleagues, she sets out on a perilous road trip to the other side of the world.

Loudun, October 1947. Leon Besnard and Marie celebrate their eighteenth wedding anniversary with friends and Ady, a former German prisoner they have "adopted". A few days later, Leon dies. Louise, a friend of the couple's and probably Leon's mistress claims that, on his deathbed, the deceased told her that Marie was poisoning him. The whole town soon condemns Marie and she is arrested and sent to jail. Did she really kill Léon as well as twelve other members of her family as she finds herself charged with?