When two grifters meet after crashing the same millionaire’s Christmas party, they agree to work together to achieve each other’s “mission,” not knowing that they would find something more than money or fame – true love.

Keller Dover is facing every parent’s worst nightmare. His six-year-old daughter, Anna, is missing, together with her young friend, Joy, and as minutes turn to hours, panic sets in. The only lead is a dilapidated RV that had earlier been parked on their street.

Left on the doorstep of an orphanage run by nuns, three newborn knuckleheads grow up to be finger-poking, nyuk-nyuking janitors named Larry, Curly and Moe. When they learn that financial problems will soon force the only home they've ever known to close, the trio sets out to raise $830,000 in one month. Out in the world for the very first time, the three innocent bumblers become embroiled in a murder plot and find stardom on a TV reality show.

Challenges of impending parenthood turn the lives of five couples upside down. Two celebrities are unprepared for the surprise demands of pregnancy; hormones wreak havoc on a baby-crazy author, while her husband tries not to be outdone by his father, who's expecting twins with his young trophy wife; a photographer's husband isn't sure about his wife's adoption plans; a one-time hook-up results in a surprise pregnancy for rival food-truck owners.

Commercial airline pilot Whip Whitaker has a problem with drugs and alcohol, though so far he's managed to complete his flights safely. His luck runs out when a disastrous mechanical malfunction sends his plane hurtling toward the ground. Whip pulls off a miraculous crash-landing that results in only six lives lost. Shaken to the core, Whip vows to get sober -- but when the crash investigation exposes his addiction, he finds himself in an even worse situation.

Beatrice Prior and Tobias Eaton venture into the world outside of the fence and are taken into protective custody by a mysterious agency known as the Bureau of Genetic Welfare.